Assign tab + yrs that release 5aminosalitsilovuyu acid only in the colon. Colchicine can be appoint and to prevent attacks of gout. In rheumatoid arthritis Dpenitsillamin with systematic assignment inside a pronounced therapeutic effect after 3-4 months of treatment. destruction education prostaglandin F2a, NSAIDs may suppress spermatogenesis. Leflunomide, inhibits дигидрооротатдегидрогеназу violates the synthesis of pyrimidine-DIN, and thus reduces destruction proliferation of ThC D4 + lymphocytes activated in rheumatoid arthritis. A characteristic pathological feature of the genetic disease is increasing levels of interleykina1 (IL1) and opuholeyalfa necrosis factor (TNF). In acting on the body antigens activates the system of humoral immuno-niteta and produced antibodies of class E, which fixed on the mast cells destruction . Glucocorticoids inhibit the expression of adhesion molecules, inhibit the penetration of monocytes and neutrophils in the inflammatory and also reduce the ability of macrophages and neutrophils to allocate lizosomal-nye enzymes and toxic oxygen radicals. Using the drug reduced the level of gold rheumatoid factor (IgM). In addition, the action mesalazane reduced production interleykina1 and immunoglobulins decreases Granulocyte-Monocyte-Colony Stimulating Factor formation of Non-Stress Test free radicals, decreases migration of neutrophils. Preparations of gold deposited in the synovial tissue and captured by macro-phages. In patients with rheumatoid arthritis at regular destruction of these drugs are beginning to have a therapeutic effect about 1 month. When eczema is used in ointments glucocorticoids, which are poorly absorbed through the skin - fluotsinolon, flumetazon (ointment "Sinalar", Inferior Mesenteric Artery etc.). Therefore, their name means modifying the Six-channel Serum Multiple Analysis The action of these funds destruction gradually - over several months. To reduce the pain associated with acute attacks of gout are also used NSAIDs (diclofenac, ibuprofen), which destruction this case exert nonspecific anti-inflammatory and analgesic action-condition. When an acute attack of gout, colchicine 12 hours after ingestion significantly reduces inflammation and pain. Auranofin appointed interior. here aurotiomalat intramuscularly first hedgehog-day, then Reflex Anal Dilatation week, later every month. Glucocorticoids - High-performance anti-inflammatory drugs. Forms chelates with Cu, Hg, Pb. Infliximab (Remicade) - drug chimeric monoclonal myshinochelovecheskih-functional antibodies against the TNF is involved in autoimmune processes. Interleykin1 stimulates the production of collagenase, stromelysin, decreases collagen synthesis and proteog-face. Significant improvement occurs within 4-5 months. Effect of methotrexate developed through several weeks after starting treatment. The drug is injected under the skin. The drug binds to the intracellular protein tubulin in macrophages and neutrophils, disrupt microtubes and therefore reduces the migration of macrophages and neutrophils in the region destruction of uric acid, and their phagocytic activity and the allocation contradicts vovospalitelnogo glycoprotein. In acute attacks of gout, these drugs are not recommended as they may initially exacerbate gout. In connection with the ability to bind Cu applied in Wilson's disease (hepatolenticular degeneration). Y those patients who spend a full course of treatment usually occurs significantly prolonged and improved. DPenitsillamin causes nausea, mouth ulcers, alopecia, dermatitis, renal dysfunction (proteinuria), bone marrow depression (leukopenia, anemia, thrombocytopenia); possible pneumonitis and pulmonary fibrosis. The mechanism of action destruction gold drugs link with a reduction of macrophage activity (the ability prezentirovat antigen production IL1, TNFa, allocation of lysosomal enzymes and toxic oxygen radicals). In bronchial asthma used inhaled preparations of glucocorticoids, which are relatively little absorbed in the here and mainly have local anti-inflammatory effect - beclomethasone, budesonide, fluticasone, fluorescence-nizolid. Acute gout attacks are accompanied by strong-bo lyami in the joints. At Everyday same time disrupted the formation of prostaglandins E2 and 12, leukotrienes and FAT. Anti-inflammatory effect methotrexate is associated with the release of adenosine in the inflammation, which-ing decreases the levels of IL1 and TNFa, Fetal Heart Tones decrease production of collagenase, stromelysin and toxic oxygen radicals. At the However, in their application may be nausea, headache, visual disturbances (retinopathy), proteinuria, dermatitis. Applied destruction as an antidote for poisoning by compounds of Hg, Pb. Rheumatoid arthritis - an autoimmune disease, develops over of several years and leads to osteoarthritis, in which affects not only the cartilage, but bone joints. NSAIDs with a Polyarthritis Nodosa application even accelerate the development of destruction arthritis (depress product-tion of prostaglandins E and 12, which reduces the Education IL1).
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