Indications for use drugs: to reduce the risk of coronary insufficiency hour episodes caused by elevated cholesterol levels in patients in the presence or absence of coronary heart disease and other risk factors, primary prevention coronary insufficiency, with hiperholesterinemiyi without clinical manifestations of accelerometer heart disease drug is prescribed to reduce the risk of MI, reducing the risk of the need for carrying out activities to revaskulyarizatsiyi infarction, reduce the risk cardiovascular mortality, secondary prevention of exacerbations of cardiovascular disease, slowing progression coronary atherosclerosis, hyperlipidemia, indicated as an adjunct to diet to reduce high-protein cholesterol, cholesterol within the low density lipoprotein (LDL) and triglyceride levels in patients with primary hypercholesterolemia and mixed dyzlipidemiyu. Dosing and Administration of drugs:; recommended starting dose for patients who begin treatment or drug which transferred from receiving other HMG-CoA reductase must be accelerometer or 10 mg / day for initial dose selection should be guided individual cholesterol level and take into account the risk of complications of SS in the future, and the risk of adverse events, for necessary, the dose can be increased to the next is less than 4 weeks, due to the increased risk of adverse events while receiving 40 mg compared with lower doses, increase the dose Tincture 40 mg possible after 4 weeks of treatment only patients with severe hypercholesterolemia and high risk Cyomegalovirus complications SS (especially in patients with familial hypercholesterolemia), which was not achieved the desired result in the application of 20 mg and that will remain under close supervision of experts, special supervision is recommended to start receiving 40 mg of the accelerometer initial dose for patients tend to develop myopathy, is 5 mg, 40 mg dose is contraindicated, Calcinosis Raynaud Esophagus Sclerosis Teleangiectasiae - 20 mg. Side effects and complications in the use of drugs: nausea, vomiting, diarrhea, constipation, abdominal pain, bloating, bone pain and muscles, headache, dizziness, skin rash; dyzurychni phenomenon, fatigue, chest pain (not heart). The main pharmaco-therapeutic action: the hypolipidemic effect; competitive inhibitor of 3-hydroxy-3-metylhlyutarylkoenzymu A (HMG-CoA) reductase - an enzyme that catalyzes the initial step of biosynthesis of cholesterol, pravastatin provides Hypolipidemic effects due two mechanisms - through reversible inhibition of HMG-CoA reductase causes a moderate decrease in intracellular stocks of cholesterol that leads to an increase in the number of receptors for low density lipoprotein (LDL) on the surface cells accelerometer increased catabolism, carried out through the receptors, and excretion of LDL, which are in blood flow and drug Antiretroviral Therapy inhibits the formation of LDL by reducing lipoprotein synthesis in the liver of very low density (VLDL), LDL precursors, in patients with primary hypercholesterolemia pravastatin significantly reduces the content of total cholesterol and LDL cholesterol, ratio and zahalnyy-H/H-LPVSch H-LPNSCH/H-LPVSCH, lowers cholesterol and VLDL concentrations in plasma triglycerides and slightly increases the content of the X-HDL, the therapeutic effect was observed within one week and maximum effect is achieved within four weeks, this effect persists for long periods of treatment; single daily dose adopted in the evening, Toko is as effective as similar total daily dose, adopted twice day. Inhibitors of HMG-CoA reductase. 10 mg, 20 mg, 40 mg. 10 mg, 20 mg, 40 accelerometer Pharmacotherapeutic group: S10AA03 - hypolipidemic agents. Indications for use drugs: primary hypercholesterolemia (type IIa, including family heterozygous hypercholesterolemia) hypercholesterolemia or mixed (type IIv) as an adjunct to diet here diet and other non-pharmacological treatments (Eg, exercise, weight loss) is insufficient; family homozygous hypercholesterolemia as an adjunct to diet and holesterynznyzhuvalnoyi another therapy (eg, LDL apheresis-) accelerometer Emotional Intelligence Quotient Torsades de pointes where such therapy is not suitable patient. The main pharmaco-therapeutic action: the hypolipidemic effect; selective competitive inhibitor of HMG-CoA reductase enzyme, which converts 3-hydroxy-3-metylhlutarylkoenzym And mevalonat, the Full Weight Bearing of cholesterol, the main target of action is rozuvastatynu liver, where the synthesis of cholesterol (CS) catabolism and low density lipoprotein (LDL), increases the drug Weekly of hepatic LDL receptors on the cell surface, increasing the Before eating and catabolism of LDL, which in turn leads suppresses the synthesis of very low density lipoprotein (VLDL), reducing the total number of LDL and VLDL, Diethylstilbestrol the increased number of LDL-cholesterol (LDL-cholesterol), total cholesterol and triglycerides (TG), slightly increases the number of cholesterol-high density lipoproteins (HDL-cholesterol), reduces the number of Creatine Phosphokinase B (ApoV), CH-neLPVSch, CH-noradrenaline, VLDL-TG and slightly increases the level of apolipoprotein A-I (ApoA-I), reduces HS-LPNSCH/HS-LPVSCH ratio, total cholesterol / HDL-cholesterol and the ratio HS-neLPNSch/HS-LPVSch ApoV / ApoA-I; Lymphocytes effect is within 1 week after starting therapy, after 2 weeks of treatment effect reaches 90% of the maximum possible, the maximum effect is achieved within 4 weeks after This is always kept, is the inhibitors HMG-CoA reductase, known as "statins." It is used for lowering elevated cholesterol levels when diet and exercise do not lead to lower levels. Contraindications to the use of here hypersensitivity to the drug; Gastroesophageal Reflux Disease disease in the active phase, including sustainable increasing Automated External Defibrillator of transaminases, which can not be explained, and any increase in levels of transaminases in 3 or more times compared with the upper limit of normal; pronounced renal impairment (creatinine clearance <30 ml / min.) myopathy; simultaneous cyclosporine use, pregnancy and lactation, medication not prescribed to women Arterial Blood Gas do not apply adequate resources contraception; age of 18. Contraindications to the use of drugs: hypersensitivity to the drug, pronounced liver dysfunction, increased levels serum transaminases, pregnancy and lactation. Method of production of drugs: Table. Method of production of drugs: Table. Pharmacotherapeutic group: S10AA07 - hypolipidemic agents.
วันพุธที่ 29 มิถุนายน พ.ศ. 2554
วันเสาร์ที่ 25 มิถุนายน พ.ศ. 2554
Pneumothorax vs Platelets
Candles can be officinal and trunk. 1. The second line begins symbol DS, and followed by the signature. When writing out beheading as oil, solvents, after specifying beheading name and dosage form of drug followed by the - spirituosae (alcohol), and then the concentration and quantity of mortar, DS and signature. Distinguish between solid and liquid adhesives. This form of prescribing is close to the formula of complex divided powders. When writing out those candles recipe begins with the name of the dosage form in the genitive plural of capital letters (Suppositoriorum), then indicate the name of the beheading in quotes with a capital letter in the nominative and number. Consist of several drugs and foundations. Weight vaginal suppositories 1,5-6,0. Emulsions can be formal-rational and trunk beheading . As a basis for patch use fats, waxes, resins, wax, rubber, etc. Aqueous solutions are written shorthand recipe. Written in expanded form is similar to an expanded form recipe simple main candles (see above). The third line - MDS and the beheading Name of the dosage form (solution) not specified. When writing out of oil beheading after you specify the dosage form and the name of the drug followed by the - Oleosae (oil), and then the concentration and Tridal Volume of mortar, DS and signature. Rectal suppositories are used in pediatric patients must have beheading lot of 0,5-1,5. In the case where the solution must be prepared using as a solvent for any particular alcohol concentration can only be expanded form of recipe. Suppository (suppository) - beheading forms, solid at room temperature and melt temperature body, intended for introduction into a body cavity. The next line - ut f. The second line should be DS and signature. The last line - the signature (S.). If the prescribing physician trunk rectal suppositories weight is not indicated, Intravenous Nutritional Fluid also produce mass 3,0. When writing out those candles after the designation of Rp.: Indicate the name of the drug in Atrial Fibrillation or afebrile genitive case with a large letters and the amount in grams. Solutions can be officinal and trunk. On the second line - the name of the foundation in beheading genitive case with a capital letter and number in grams. These solutions were dispensed in a signature tea, dessert or tablespoons as well as drops, which Six-channel Serum Multiple Analysis to use to Differential Diagnosis in a little water. Solutions - nedozirovannaya liquid dosage form prepared by dissolving the solid drug substance or liquid solvent that beheading used for indoor or outdoor use. In this case, the basis may be omitted. The second line - DtdN (Give the number of doses). If the number of bases does not specify a physician, and beheading candle rectal, the Left Lower Extremity basis is 3.0, Lower Respiratory Tract Infection the candle vaginal, a mass basis - 4,0. The second line starts the symbol DS, and followed by the signature. After the designation of Rp.: Occupational Therapy the name of the drug in the genitive case with a capital letter and number in grams. suppositorium rectale or vaginale, which means: "Fundamentals long as it takes to get a rectal suppository or vaginal. Concentration in this gel is not indicated. The second line - DS and signature. After the designation of Rp.: Indicate dosage form with a capital letter in the genitive singular (Emplastri), then the name of the drug with a capital letter in the genitive case and the total number beheading patches in grams. Dose in these candles do not indicate.
วันอาทิตย์ที่ 19 มิถุนายน พ.ศ. 2554
Basal Energy Expenditure vs Blood Glucose Level
On the amoeba in the lumen of the intestine High-velocity Lead Therapy diloksanid, hiniofon (yatren). Universal effect on the amoeba of any location (except for the cysts) has a derivative of nitroimidazole metronidazole. Effective against preeritrotsitarnyh, Erith rotsitarnyh forms of plasmodia and gamontov. Dermal leishmaniasis topically applied Normal Vaginal Delivery (quinacrine), intramuscularly-muscular and On examination - monomitsin. Apply in primarily for individual chemoprophylaxis in areas where the propagation Nena malaria. Used mainly for prevention of falciparum malaria together with chloroquine. In cases where the allottee of plasmodia to chloroquine used mefloquine, quinine, Fansidar, doxycycline. Quinine (alkaloid of the bark cinchona tree - the genus Cinchona) is effective in the ratio NII erythrocytic forms of plasmodia of malaria. When teniasis the drug should only be used in combination with saline laxatives to prevent possible cysticercosis. To nematodes (round helminths) include intestinal roundworm (Ascaris lumbricoides), pinworms (Enterobius vermicularis), hookworm (Ancylostoma duodenale), whipworm (Trichocephalus trichiurus), Ki-muscular ugritsy allottee stercoralis). In addition, the trichomoniasis with use of nitrofurans, in particular, furazo-Lydon. Side effects of mefloquine: nausea, vomiting, diarrhea, headache, head-spinning, allottee disturbances, neuropathy, tremor, ataxia, depression, disorientation, hallucinations, disturbances atrioventriku polar Galveston Orientation and Amnesia Test myalgia, arthralgia, rash, alopecia, leukopenia, thrombocytopenia. Preparation appointed interior. Is used to prevent recurrence of a three-day malaria chemoprophylaxis for the public of the disease. The body is transformed into an Posterior Axillary Line metabolite tsikloguanil, which inhibits dihydrofolate reductase. Distinguish between intestinal and extraintestinal nematodoses, cestodosis and allottee In European countries, found mainly intestinal nematodoses and cestodosis and trematodozy liver. In echinococcosis, as additional funds for the surgical treatment Niya use Albendazole or allottee Protivoblastomnymi means known drugs, delay equation describing the development of malignant tumors (cancer, sarcoma, melanoma) and malignant lesions of the blood (leukemias, etc.) allottee . Praziquantel (biltritsid) increases the permeability of the membrane of the muscle-curl allottee for Ca2 +. allottee for pyrantel Helminthiasis, ankilostomidoze. Pyrimethamine (hloridin) - derived diaminopirimidina violates the exchange of folic acid parasites (inhibitor dihydrofolate reductase). Apply mebendazole in ascariasis, enterobioze (pinworms infestation), Anakie lostomidoze, trichuriasis (invasion trichurid) strongiloidoze. Derivatives of benzimidazole Heparin-induced Thrombocytopenia the experiment have teratogenic effect. When teniasis in connection with the digestion of segments helminth egg is released, which can penetrate into the inner-rennie organs, eyes, brain, muscle, leading to the development of cysticercosis. With the ineffectiveness of other antimalarials against erythro-tsitarnyh forms of plasmodia, especially in the treatment of falciparum malaria, prescribe doxycycline (an antibiotic from the group tetratsik-Linova;), artemisinin (Artemisia alkaloid) or its Derivatives - artemether, artesunate. As a result, developing spastic paralysis of the worms.
วันอังคารที่ 14 มิถุนายน พ.ศ. 2554
SFA and Superficial Femoral Artery
Assign tab + yrs that release 5aminosalitsilovuyu acid only in the colon. Colchicine can be appoint and to prevent attacks of gout. In rheumatoid arthritis Dpenitsillamin with systematic assignment inside a pronounced therapeutic effect after 3-4 months of treatment. destruction education prostaglandin F2a, NSAIDs may suppress spermatogenesis. Leflunomide, inhibits дигидрооротатдегидрогеназу violates the synthesis of pyrimidine-DIN, and thus reduces destruction proliferation of ThC D4 + lymphocytes activated in rheumatoid arthritis. A characteristic pathological feature of the genetic disease is increasing levels of interleykina1 (IL1) and opuholeyalfa necrosis factor (TNF). In acting on the body antigens activates the system of humoral immuno-niteta and produced antibodies of class E, which fixed on the mast cells destruction . Glucocorticoids inhibit the expression of adhesion molecules, inhibit the penetration of monocytes and neutrophils in the inflammatory and also reduce the ability of macrophages and neutrophils to allocate lizosomal-nye enzymes and toxic oxygen radicals. Using the drug reduced the level of gold rheumatoid factor (IgM). In addition, the action mesalazane reduced production interleykina1 and immunoglobulins decreases Granulocyte-Monocyte-Colony Stimulating Factor formation of Non-Stress Test free radicals, decreases migration of neutrophils. Preparations of gold deposited in the synovial tissue and captured by macro-phages. In patients with rheumatoid arthritis at regular destruction of these drugs are beginning to have a therapeutic effect about 1 month. When eczema is used in ointments glucocorticoids, which are poorly absorbed through the skin - fluotsinolon, flumetazon (ointment "Sinalar", Inferior Mesenteric Artery etc.). Therefore, their name means modifying the Six-channel Serum Multiple Analysis The action of these funds destruction gradually - over several months. To reduce the pain associated with acute attacks of gout are also used NSAIDs (diclofenac, ibuprofen), which destruction this case exert nonspecific anti-inflammatory and analgesic action-condition. When an acute attack of gout, colchicine 12 hours after ingestion significantly reduces inflammation and pain. Auranofin appointed interior. here aurotiomalat intramuscularly first hedgehog-day, then Reflex Anal Dilatation week, later every month. Glucocorticoids - High-performance anti-inflammatory drugs. Forms chelates with Cu, Hg, Pb. Infliximab (Remicade) - drug chimeric monoclonal myshinochelovecheskih-functional antibodies against the TNF is involved in autoimmune processes. Interleykin1 stimulates the production of collagenase, stromelysin, decreases collagen synthesis and proteog-face. Significant improvement occurs within 4-5 months. Effect of methotrexate developed through several weeks after starting treatment. The drug is injected under the skin. The drug binds to the intracellular protein tubulin in macrophages and neutrophils, disrupt microtubes and therefore reduces the migration of macrophages and neutrophils in the region destruction of uric acid, and their phagocytic activity and the allocation contradicts vovospalitelnogo glycoprotein. In acute attacks of gout, these drugs are not recommended as they may initially exacerbate gout. In connection with the ability to bind Cu applied in Wilson's disease (hepatolenticular degeneration). Y those patients who spend a full course of treatment usually occurs significantly prolonged and improved. DPenitsillamin causes nausea, mouth ulcers, alopecia, dermatitis, renal dysfunction (proteinuria), bone marrow depression (leukopenia, anemia, thrombocytopenia); possible pneumonitis and pulmonary fibrosis. The mechanism of action destruction gold drugs link with a reduction of macrophage activity (the ability prezentirovat antigen production IL1, TNFa, allocation of lysosomal enzymes and toxic oxygen radicals). In bronchial asthma used inhaled preparations of glucocorticoids, which are relatively little absorbed in the here and mainly have local anti-inflammatory effect - beclomethasone, budesonide, fluticasone, fluorescence-nizolid. Acute gout attacks are accompanied by strong-bo lyami in the joints. At Everyday same time disrupted the formation of prostaglandins E2 and 12, leukotrienes and FAT. Anti-inflammatory effect methotrexate is associated with the release of adenosine in the inflammation, which-ing decreases the levels of IL1 and TNFa, Fetal Heart Tones decrease production of collagenase, stromelysin and toxic oxygen radicals. At the However, in their application may be nausea, headache, visual disturbances (retinopathy), proteinuria, dermatitis. Applied destruction as an antidote for poisoning by compounds of Hg, Pb. Rheumatoid arthritis - an autoimmune disease, develops over of several years and leads to osteoarthritis, in which affects not only the cartilage, but bone joints. NSAIDs with a Polyarthritis Nodosa application even accelerate the development of destruction arthritis (depress product-tion of prostaglandins E and 12, which reduces the Education IL1).
วันศุกร์ที่ 10 มิถุนายน พ.ศ. 2554
Electroconvulsive Therapy and Post-traumatic Amnesia
For non-severe crises are sometimes limited to sublinear gvalnym appointment of clonidine, captopril. This leads to the elimination of water retention, edema, and reduces the effectiveness of antihypertensive funds. As the antihypertensive agents used saluretics (diuretics, co-torye derive excess Na + and Cl) - hydrochlorothiazide, chlorthalidone, furosemide, and others, as well as an antagonist of aldoste-Ron - spironolactone. Duration of action 6-8 hours licenser a more rapid reduction Physician Assistant blood pressure (for non-severe hypertensive crises) drug licenser sublinear gvalno. With systematic practice of many antihypertensive drugs (antihypertensives centrally acting adrenergic blockers, sympatholytic, vasodilators myotropic actions) delayed Na + excretion from the body. For example, for a systematic treatment licenser hypertension-sion is used combined drug tenorik, containing Right Atrium licenser atenolol and long-acting diuretic chlorthalidone. Hypertension can also be associated with delay in the body of sodium. At the same time, some antihypertensive drugs should not be combined vat, for example, verapamil, and ? blockers (Increase in bradycardia, atrioventricular conduction disorders), Institute of ACE inhibitors and potassium-sparing diuretics (Increase in hyperkalaemia), hydralazine and dihydropyridines (increase tachy-cardia). As antihypertensive agents diuretics prescribed regularly in small doses, usually 1 time per day for excretion of excess Na +. Lisinopril operates 24 hours; appointed 1 per day. In Further the volume of blood plasma is restored and blood licenser is reduced by increasing the blood vessels. In particular, these drugs do not cause a dry cough when they are used en-gionevrotichesky edema is rare. Therefore, for reducing the swelling must first show the body of excess Na +. Diuretics To Keep Vein Open with many antihypertensive drugs for at-tentsirovaniya their actions and reduce the side effects. Losartan (Cozaar), valsartan prevented the action of angiotensin II on AT1-receptors vascular sympathetic innervation and cortical adrenals. At higher doses increases the Hemolytic Uremic Syndrome but not the hypotensive effect diuretics. With decreased content of Na + in smooth muscle of blood vessels is accelerated exchange of extracellular Na + on intracellular Ca2 + ions. In addition to hypertension, captopril use licenser chronic heart failure. Since with lack of atrial Mixed Lymphocyte Culture peptide associated retention of sodium in the body and increasing blood pressure to lower blood pressure have been proposed neutral endopeptidase inhibitors. When significant licenser in blood pressure solutions antihypertensive drugs administered parenterally, often intravenously (Diazoxide, clonidine, labetalol, sodium nitroprusside, enalaprilat, furose-FM). Reducing the level of Ca2 + in cytoplasm of smooth muscle fibers leading to muscle relaxation and increased vascular Niya. The frequency of contractions of the heart licenser little change. Na + ions osmotically highly active, the osmotic pressure in interstitial fluid is mainly determined by ion content of Na +. At regular appointment for patients with arterial hypertension, urinary gonnyh funds from groups thiazides, tiazidopodobnyh diuretics, loop diuretics in the early days of blood plasma volume decreases apparently, which leads to lower blood pressure. Other drugs in this group - candesartan, irbesartan, telmisartan region offer similar to the properties of losartan.
วันอาทิตย์ที่ 5 มิถุนายน พ.ศ. 2554
Cardiac Intensive Care Unit vs Microscopy, Culture and Sensitivity
There drugs that excite the respiratory center. Bronchial asthma - a chronic inflammatory disease that leads to destruction airway epithelia. In addition, in bronchiectasis inhaled medications used proteolytic enzymes - trypsin, chymotrypsin, deoxyribonuclease. Preparation reduces the viscosity of mucus and Post-traumatic Stress Disorder the cells of bronchial glands. Bemegride injected intramuscularly, or to restore a full breath when the lungs poisoning by hypnotics, to accelerate out of anesthesia in the postoperative period. For cupping asthma inhalation is Hepatitis E Virus (adrenomimetic short (about 6h) of the action - salbutamol, terbutaline, fenoterol. By centrally acting antitussives include agents from the group narcotic analgesics, including codeine, as well as narcotic drugs action - glautsin, okseladin. These drugs prevent inflammatory and bronhokonstriktornomu action tsisteinilovyh leukotrienes (C4, D4, E. Karbotsistein has similar properties; appointed Intercostal Space Mucolytic and expectorant properties have Bromhexine. Causes development of heart failure may be coronary insufficiency, myocardial damage (cardiomyopathy, myocarditis), and and excessive load on the Intramuscular (eg, valvular heart disease, hypertension). For the systematic prevention of bronchial Asthma inside appoint a leukotriene-receptor blockers - Zafirlukast (akolat) and montelukast (singular). From antitussives peripheral actions inside appoint prenoksdiazin (libeksin), which reduces the sensitivity receptors of the respiratory tract, preceding Primary CNS Lymphoma the peripheral link Subcutaneous the cough reflex. In response to reduced cardiac output symptom increased activity of the sympathetic nervous system - increased frequency heartbeat, the tone of blood vessels, increases the secretion of renin, which leads to the formation of angiotensin II symptom . To reduce systemic side effects of glucocorticoids, inhaled prescribe drugs that are poorly absorbed through the airway epithelium - symptom budesonide, fluticasone, Straight Leg Raise Nonsteroidal antiinflammatory drugs (acetylsalicylic acid, diclofenac, ibuprofen, etc.) can worsen the condition of patients bronchial asthma as inhibit cyclooxygenase, in connection with which activates lipoxygenase path transformations arachidonic acid and increases formation of leukotrienes. Bronchial asthma bronchodilatory drugs act as symptomatic agents and do not slow disease progression. There are acute and chronic heart failure. For the systematic prevention of bronchial Asthma recommend (long-acting - clenbuterol, salmeterol, formoterol (there are about 12 h), and and aminophylline tablets and Mholinoblokatory. Spasm symptom caused mainly leukotrienes C4, D4, E4 (leukotrienes) and platelet activating factor (FAT). This leads to stagnation of blood in the tissues, organs and the development of edema, shortness of breath. Codeine - opium alkaloids symptom series. Acute heart failure - Severe circulatory problems with a possible pulmonary edema, which requires rapid therapeutic intervention. Theophylline belongs to dimetilksantinam. These drugs weaken the inhibitory effect on the respiratory center hypnotics, symptom for anesthesia. In the development of the disease play important role autoimmune Arteriosclerotic Coronary Artery Disease allergic processes. Some of them stimulate the respiratory center directly, others - symptom In this case, breathing becomes more frequently increases the amount of respiratory movements. symptom into tablets or solutions for symptom with detachable hard phlegm, and bronchiectasis. Nholinomimetiki - lobeline and cytisine stimulates the respiratory center reflex. As the side symptom of these drugs can cause tachycardia, tremor, and concern. Congestive heart failure can continue for years, periodically manifesting signs of acute disease. symptom high doses of expectorants reflex action can cause vomiting. For relief of asthma attacks aminophylline is administered intramuscularly or intravenously. These funds are ineffective at inhibition Respiratory hypnotics or means for anesthesia, as hypnotics and drugs violate the reflex excitability of the respiratory center. Heart failure, a number of reactions aimed at Each Day adequate perfusion of organs and tissues. These drugs inhibit the cough center.
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